Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666689 | 0.91 | CHRM1 (0.46) | CHRM1HRH1 | |
| SCHEMBL7676736 | 0.91 | CHRM1 (0.36) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL7658335 | 0.90 | CHRM1 (0.48) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL7665232 | 0.89 | CHRM1 (0.37) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL7665227 | 0.89 | CHRM1 (0.37) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL6998924 | 0.86 | CHRM1 (0.38) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL6995745 | 0.79 | DRD2 (0.61) | DRD4CHRM1DRD2DRD3ADRA2A | |
| Fumaric Acid SCHEMBL7671580 | 0.73 | CHRM1 (0.41) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL6998224 | 0.72 | DRD2 (0.53) | DRD4CHRM1DRD2DRD3ADRA2A | |
| SCHEMBL6991310 | 0.72 | DRD2 (0.61) | DRD4CHRM1DRD2DRD3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455521-B1 | PSYCHOLOGICAL DISORDERS; SIDE EFFECT REDUCTION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| US-6271225-B1 | PSYCHOLOGICAL DISORDERS | WELFIDE CORPORATION (JP) | 2001-08-07 | — | — | US | disclosed |