Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665227 | 1.00 | CHRM1 (0.37) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL7666689 | 0.91 | CHRM1 (0.46) | CHRM1HRH1PAK1 | |
| SCHEMBL7676736 | 0.89 | CHRM1 (0.36) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL7653477 | 0.89 | DRD4 (0.44) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL7658335 | 0.88 | CHRM1 (0.48) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL6998924 | 0.86 | CHRM1 (0.38) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL6990288 | 0.80 | CHRM1 (0.48) | CHRM1DRD2DRD4DRD3HRH1 | |
| Maleic Acid SCHEMBL7666335 | 0.71 | CHRM1 (0.41) | CHRM1DRD2DRD4DRD3HRH1 | |
| Maleic Acid SCHEMBL7967787 | 0.70 | HRH1 (0.40) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL6996799 | 0.69 | CHRM1 (0.58) | CHRM1HRH1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455521-B1 | PSYCHOLOGICAL DISORDERS; SIDE EFFECT REDUCTION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |