Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17892066 | 0.84 | MEN1 (0.50) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL7678705 | 0.82 | UGT2B7 (0.47) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL6008493 | 0.76 | UGT2B7 (0.52) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL7435867 | 0.76 | UGT2B7 (0.52) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL7436041 | 0.76 | UGT2B7 (0.52) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL5408505 | 0.75 | UGT2B7 (0.55) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL5401290 | 0.73 | UGT2B7 (0.59) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL16684715 | 0.73 | UGT2B7 (0.59) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL9592384 | 0.72 | UGT2B7 (0.52) | UGT2B7AOC3MEN1KMT2AATM | |
| SCHEMBL10120474 | 0.72 | UGT2B7 (0.62) | UGT2B7AOC3MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |