Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581857 | 0.83 | KMT2A (0.58) | RAB9ALMNAPDE1CPOLBITGA4 | |
| SCHEMBL6536499 | 0.82 | ALDH1A1 (0.48) | RAB9ALMNAPOLBMAPTKMT2A | |
| SCHEMBL6647431 | 0.82 | TDP1 (0.47) | RAB9ALMNAPOLBMAPTKMT2A | |
| SCHEMBL6686530 | 0.82 | POLB (0.45) | LMNAPOLBMAPTKMT2AMEN1 | |
| SCHEMBL6536275 | 0.81 | TDP1 (0.46) | RAB9ALMNAPOLBMAPTKMT2A | |
| SCHEMBL7663538 | 0.81 | TDP1 (0.46) | RAB9APOLBMAPTKMT2ATDP1 | |
| SCHEMBL17202449 | 0.81 | RAB9A (0.47) | RAB9ALMNAPDE1CPOLBITGA4 | |
| SCHEMBL31656228 | 0.81 | RAB9A (0.54) | RAB9ALMNAPDE1CPOLBITGA4 | |
| SCHEMBL27137411 | 0.81 | RAB9A (0.54) | RAB9ALMNAPDE1CPOLBITGA4 | |
| SCHEMBL15754683 | 0.81 | RAB9A (0.54) | RAB9ALMNAPDE1CPOLBITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |