Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650864 | 0.92 | TP53 (0.51) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL6652586 | 0.91 | KMT2A (0.60) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL7649849 | 0.90 | KMT2A (0.55) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL7646312 | 0.86 | APP (0.46) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL7651874 | 0.83 | ATM (0.46) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL7553839 | 0.82 | APP (0.49) | APPKMT2APOLBRAD52HTT | |
| SCHEMBL9821131 | 0.82 | KMT2A (0.59) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL6658584 | 0.82 | HSD17B10 (0.51) | APPKMT2APOLBRAD52MEN1 | |
| Hydrochloric Acid SCHEMBL9821072 | 0.81 | KMT2A (0.57) | APPKMT2APOLBRAD52MEN1 | |
| SCHEMBL6651230 | 0.81 | APP (0.47) | APPKMT2APOLBRAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339077-B1 | FOR PROPHYLAXIS OR OF GALLSTONES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-15 | — | — | US | disclosed |