Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649849 | 0.87 | KMT2A (0.55) | SMN1; SMN2KMT2ALMNAGLAMEN1 | |
| SCHEMBL7653573 | 0.83 | APP (0.52) | SMN1; SMN2KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7646312 | 0.83 | APP (0.46) | SMN1; SMN2KMT2ALMNAGLAMEN1 | |
| SCHEMBL6650864 | 0.82 | TP53 (0.51) | SMN1; SMN2KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7646678 | 0.79 | KMT2A (0.61) | SMN1; SMN2KMT2ALMNAGLAMEN1 | |
| SCHEMBL7650263 | 0.76 | MAPT (0.53) | SMN1; SMN2KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7553839 | 0.76 | APP (0.49) | SMN1; SMN2KMT2ALMNAGLAAPP | |
| SCHEMBL7651486 | 0.75 | PRNP (0.50) | SMN1; SMN2KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL6652586 | 0.75 | KMT2A (0.60) | SMN1; SMN2KMT2AMEN1ALDH1A1APP | |
| SCHEMBL6651230 | 0.74 | APP (0.47) | SMN1; SMN2KMT2ALMNAGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339077-B1 | FOR PROPHYLAXIS OR OF GALLSTONES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-15 | — | — | US | disclosed |