⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079865 | 0.91 | KDM4E (0.51) | — | |
| SCHEMBL11080389 | 0.85 | HSD17B10 (0.41) | — | |
| SCHEMBL2557014 | 0.82 | L3MBTL1 (0.42) | — | |
| SCHEMBL24461602 | 0.80 | — | — | |
| SCHEMBL10686156 | 0.79 | HSD17B10 (0.38) | — | |
| SCHEMBL7289985 | 0.79 | POLB (0.49) | — | |
| SCHEMBL1701604 | 0.79 | POLB (0.49) | — | |
| SCHEMBL15447586 | 0.79 | POLB (0.49) | — | |
| SCHEMBL8406208 | 0.79 | POLB (0.49) | — | |
| SCHEMBL15438887 | 0.79 | POLB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174653-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | US | disclosed |
| EP-2207775-B1 | 4-BENZYLAMINO-1-CARBOXYACYL-PIPERIDINE DERIVATIVES AS CETP INHIBITORS USEFUL FOR THE TREATMENT OF DISEASES SUCH AS HYPERLIPIDEMIA OR ARTERIOSCLEROSIS | NOVARTIS AG (CH) | 2012-03-21 | — | — | EP | disclosed |