Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | UBE2N | P61088 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7651119 | 0.99 | BCHE (0.51) | BCHEMEN1UBE2NKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7650024 | 0.92 | BCHE (0.53) | BCHEMEN1UBE2NKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7658024 | 0.91 | BCHE (0.53) | BCHEMEN1UBE2NKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7650323 | 0.86 | UBE2N (0.51) | BCHEMEN1UBE2NKMT2ALMNA | |
| SCHEMBL7648340 | 0.85 | BCHE (0.49) | BCHEMEN1UBE2NKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7651115 | 0.85 | BCHE (0.48) | BCHEMEN1UBE2NKMT2ALMNA | |
| SCHEMBL7657482 | 0.83 | KCNA3 (0.47) | BCHEMEN1UBE2NKMT2ALMNA | |
| SCHEMBL7652144 | 0.83 | BCHE (0.51) | BCHEMEN1UBE2NKMT2ALMNA | |
| SCHEMBL7649983 | 0.82 | BCHE (0.50) | BCHEMEN1UBE2NKMT2ALMNA | |
| SCHEMBL7652044 | 0.82 | CACNA1G (0.53) | BCHEMEN1UBE2NKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407116-B1 | 2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINE DERIVATIVES; ANTIALLERGENS, ANTIASTHMATICS, ANTIHISTAMINES, AND ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1026160-A1 | NITROGENOUS FUSED-RING COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |