Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661164 | 1.00 | MEN1 (0.39) | MEN1ALDH1A1KMT2AMAPTPKM | |
| SCHEMBL4442002 | 0.84 | MAOA (0.45) | MEN1ALDH1A1KMT2AMAPTPKM | |
| SCHEMBL13211923 | 0.84 | ELANE (0.41) | MEN1KMT2AGPR84PTGS2HSD17B3 | |
| SCHEMBL28840682 | 0.83 | ELANE (0.42) | MEN1KMT2AMAPTGPR84PTGS2 | |
| SCHEMBL12831509 | 0.79 | GPR84 (0.35) | GPR84PTGS2MAOAMAOBKDM1A | |
| SCHEMBL11025756 | 0.77 | KDM1A (0.46) | GPR84PTGS2MAOBKDM1ATSHR | |
| Acetic Acid Phenyl Ester SCHEMBL17274565 | 0.76 | ELANE (0.45) | MEN1ALDH1A1KMT2AMAPTPKM | |
| SCHEMBL8569166 | 0.76 | PTGS2 (0.49) | ALDH1A1GPR84PTGS2MAOBKDM1A | |
| SCHEMBL30661162 | 0.76 | PTGS2 (0.49) | ALDH1A1GPR84PTGS2MAOBKDM1A | |
| SCHEMBL7080281 | 0.73 | ALOX5 (0.50) | MEN1ALDH1A1KMT2AMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992591-A | Preparation of alpha-(3,4-disubstituted aryl) cyclic ketones | SCHERING CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |