Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PTEN | P60484 | 1/20 | 0.39 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107398 | 1.00 | CYP4F2 (0.41) | CYP4F2CYP4A11KEAP1EPORFFAR1 | |
| Tert-Butylamine SCHEMBL7657274 | 0.94 | CYP4F2 (0.39) | CYP4F2CYP4A11KEAP1EPORFFAR1 | |
| Tert-Butylamine SCHEMBL7657269 | 0.94 | CYP4F2 (0.39) | CYP4F2CYP4A11KEAP1EPORFFAR1 | |
| SCHEMBL7111901 | 0.93 | HDAC3 (0.43) | CYP4F2CYP4A11EPORFFAR1MAOB | |
| SCHEMBL7657160 | 0.93 | HDAC3 (0.43) | CYP4F2CYP4A11EPORFFAR1MAOB | |
| Tert-Butylamine SCHEMBL7657275 | 0.88 | HDAC3 (0.39) | CYP4F2CYP4A11EPORFFAR1MAOB | |
| SCHEMBL7109965 | 0.87 | FFAR1 (0.45) | KEAP1FFAR1 | |
| SCHEMBL7107759 | 0.83 | MMP1 (0.47) | EPORMAOBAKR1B10AKR1B1MMP1 | |
| SCHEMBL7657096 | 0.80 | PPARA (0.50) | EPORFFAR1MAOBKDM4EALDH1A1 | |
| SCHEMBL7111045 | 0.80 | PPARA (0.50) | EPORFFAR1MAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | claimed |
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | disclosed |