Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653702 | 0.87 | CYP4F2 (0.41) | FFAR1KEAP1 | |
| SCHEMBL7107398 | 0.87 | CYP4F2 (0.41) | FFAR1KEAP1 | |
| Tert-Butylamine SCHEMBL7657269 | 0.81 | CYP4F2 (0.39) | FFAR1KEAP1FFAR4 | |
| Tert-Butylamine SCHEMBL7657274 | 0.81 | CYP4F2 (0.39) | FFAR1KEAP1FFAR4 | |
| SCHEMBL7657160 | 0.80 | HDAC3 (0.43) | FFAR1S1PR1S1PR3 | |
| SCHEMBL7111901 | 0.80 | HDAC3 (0.43) | FFAR1S1PR1S1PR3 | |
| SCHEMBL7106873 | 0.77 | FFAR1 (0.44) | FFAR1FFAR4 | |
| SCHEMBL7107759 | 0.75 | MMP1 (0.47) | — | |
| Tert-Butylamine SCHEMBL7657275 | 0.75 | HDAC3 (0.39) | FFAR1S1PR1 | |
| SCHEMBL7111045 | 0.74 | PPARA (0.50) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |