Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | APEX1 | P27695 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15663784 | 0.97 | ACHE (0.61) | ACHELMNATSHRCHRM2CHRM4 | |
| SCHEMBL7648496 | 0.92 | ACHE (0.54) | ACHELMNATSHRCHRM2CHRM4 | |
| SCHEMBL5703528 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8501382 | 0.83 | CHRM5 (0.50) | ACHELMNATSHRCHRM2CHRM4 | |
| SCHEMBL1568811 | 0.79 | ACHE (0.52) | ACHELMNATSHRCHRM2CHRM4 | |
| SCHEMBL172269 | 0.78 | ACHE (0.64) | ACHELMNATSHRMEN1KMT2A | |
| SCHEMBL14902539 | 0.78 | ACHE (1.00) | ACHELMNATSHRCHRM2CHRM4 | |
| Hexamethonium SCHEMBL1618254 | 0.78 | MEN1 (0.61) | ACHELMNATSHRCHRM2CHRM4 | |
| Octadecanoic Acid Amide SCHEMBL27994152 | 0.77 | SOAT1 (0.57) | TSHRCYP2C19MEN1KMT2AKDM4E | |
| SCHEMBL27595241 | 0.77 | SOAT1 (0.57) | TSHRCYP2C19MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002536440-A | — | — | 2002-10-29 | — | — | JP | claimed |
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | claimed |
| CN-109312277-A | Improve the first film of the sealing intensity of water soluble unit dose product and the purposes of the second film | 蒙诺苏尔有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-102791747-B | Gel polymer electrolyte composition | KURARAY CO | 2014-08-06 | — | — | CN | disclosed |
| WO-2013064450-A1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| CN-102791747-A | Gel polymer electrolyte composition | KURARAY CO | 2012-11-21 | — | — | CN | disclosed |