Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.50 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.50 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.50 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5703528 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15663784 | 0.86 | ACHE (0.61) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7653709 | 0.83 | ACHE (0.64) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7648496 | 0.81 | ACHE (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10257145 | 0.80 | BBOX1 (0.38) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10257137 | 0.80 | CYP2C19 (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Choline SCHEMBL28036788 | 0.76 | CYP3A4 (0.68) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL1705678 | 0.75 | SOAT1 (0.55) | CYP2C19TSHRCYP3A4ALDH1A1MEN1 | |
| Octadecanoic Acid Amide SCHEMBL5346586 | 0.75 | SOAT1 (0.55) | CYP2C19TSHRCYP3A4ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28807747 | 0.75 | SOAT1 (0.55) | CYP2C19TSHRCYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111469502-A | Preparation method of antibacterial and anti-mite intelligent home textile fabric | 上海龙头纺织科技有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-110524969-A | Ventilative wind-proof man textile fabric | LI JINDI | 2019-12-03 | — | — | CN | claimed |
| CN-110524969-B | Breathable and windproof home textile fabric | 江苏大毛牛新材料有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-111469502-A | Preparation method of antibacterial and anti-mite intelligent home textile fabric | 上海龙头纺织科技有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-110524969-A | Ventilative wind-proof man textile fabric | LI JINDI | 2019-12-03 | — | — | CN | disclosed |
| EP-0629399-B1 | Treatment and control of ocular development with cholinergic agonists | UNIV PENNSYLVANIA (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5637604-A | ADMINISTERING CHOLINERGIC AGONIST | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0629399-A1 | Treatment and control of ocular development with cholinergic agonists | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5360801-A | Axial elongation by administering cholinergic agent | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-11-01 | — | — | US | disclosed |
| US-5356892-A | Administering anticholinergic muscarinic antagonist to control abnormal postnatal growth of eye of animal | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-10-18 | — | — | US | disclosed |
| WO-1994015611-A1 | PHARMACOLOGICAL STIMULATION OF EYE GROWTH | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-07-21 | — | — | WO | disclosed |
| EP-0478694-A4 | TREATMENT AND CONTROL OF OCULAR DEVELOPMENT | UNIV PENNSYLVANIA (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5122522-A | Administering pirenzepine | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0478694-A1 | TREATMENT AND CONTROL OF OCULAR DEVELOPMENT. | UNIV PENNSYLVANIA (US) | 1992-04-08 | — | — | EP | disclosed |
| WO-1990015604-A1 | TREATMENT AND CONTROL OF OCULAR DEVELOPMENT | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1990-12-27 | — | — | WO | disclosed |