Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655407 | 0.86 | CYP1A2 (0.51) | NPC1KDM4ERAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7659555 | 0.84 | AOC3 (0.53) | NPC1KMT2AKDM4ERAB9AALDH1A1 | |
| SCHEMBL7653004 | 0.81 | NPC1 (0.49) | WDR5NPC1KMT2AKDM4ERAB9A | |
| SCHEMBL20339258 | 0.80 | NPC1 (0.54) | WDR5NPC1KMT2AKDM4ERAB9A | |
| SCHEMBL14992778 | 0.79 | AOC3 (0.63) | — | |
| SCHEMBL7662821 | 0.79 | NPC1 (0.53) | WDR5NPC1KMT2AKDM4ERAB9A | |
| SCHEMBL13149365 | 0.77 | SLC6A7 (0.70) | KMT2AKDM4EALDH1A1SLC6A7HPGD | |
| SCHEMBL382272 | 0.77 | ALDH1A1 (0.59) | WDR5NPC1KMT2AKDM4ERAB9A | |
| SCHEMBL24495621 | 0.77 | ALDH1A1 (0.53) | WDR5NPC1KMT2AKDM4ERAB9A | |
| SCHEMBL381751 | 0.76 | ALDH1A1 (0.61) | WDR5NPC1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451800-B1 | Phenylpiperazine derivatives as integrin αvβ3 antagonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-09-17 | — | — | US | disclosed |
| EP-1057818-A1 | PHENYLPIPERAZINE DERIVATIVES AS INTEGRIN ALPHAvBETA3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |