Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.65 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TYMS | P04818 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632480 | 1.00 | RNASE1 (0.65) | RNASE1TK1BCHEPOLBTYMS | |
| SCHEMBL6842685 | 1.00 | RNASE1 (0.65) | RNASE1TK1BCHEPOLBTYMS | |
| SCHEMBL2623807 | 1.00 | RNASE1 (0.65) | RNASE1TK1BCHEPOLBTYMS | |
| SCHEMBL13273272 | 1.00 | RNASE1 (0.65) | RNASE1TK1BCHEPOLBTYMS | |
| SCHEMBL30698170 | 0.91 | RNASE1 (0.61) | RNASE1TK1BCHETYMSUPP1 | |
| SCHEMBL6542150 | 0.91 | RNASE1 (0.61) | RNASE1TK1BCHETYMSUPP1 | |
| SCHEMBL22992340 | 0.89 | RNASE1 (0.82) | RNASE1TK1 | |
| SCHEMBL9326675 | 0.89 | RNASE1 (0.82) | RNASE1TK1 | |
| SCHEMBL13273344 | 0.89 | RNASE1 (0.68) | RNASE1POLBTYMS | |
| SCHEMBL21886791 | 0.89 | RNASE1 (0.82) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204415-A2 | 5-(E)-BROMOVINYL URACIL ANALOGUES AND RELATED PYRIMIDINE NUCLEOSIDES AS ANTI-VIRAL AGENTS AND METHODS OF USE | YALE UNIVERSITY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001006986-A2 | 5-(E)-BROMOVINYL URACIL ANALOGUES AND RELATED PYRIMIDINE NUCLEOSIDES AS ANTI-VIRAL AGENTS AND METHODS OF USE | YALE UNIVERSITY (US) | 2001-02-01 | — | — | WO | disclosed |