Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.82 |
| ▸ | TK1 | P04183 | 5/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | TK2 | O00142 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976654 | 1.00 | RNASE1 (0.82) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL9326675 | 1.00 | RNASE1 (0.82) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL10664373 | 1.00 | RNASE1 (0.82) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL9324478 | 1.00 | RNASE1 (0.82) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL21886791 | 1.00 | RNASE1 (0.82) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL13273339 | 1.00 | RNASE1 (0.82) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL11877506 | 0.91 | RNASE1 (0.68) | RNASE1TK1ABCG2ABCB1 | |
| SCHEMBL14222577 | 0.91 | RNASE1 (0.68) | RNASE1TK1ABCG2ABCB1 | |
| SCHEMBL5710067 | 0.91 | RNASE1 (0.68) | RNASE1TK1ABCG2ABCB1TK2 | |
| SCHEMBL7875892 | 0.90 | RNASE1 (1.00) | RNASE1TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |