Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814042 | 0.91 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7162115 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7656841 | 0.76 | KMT2A (0.54) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7638965 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7665509 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7904759 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7643242 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6814929 | 0.71 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7161939 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7651702 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |