Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814042 | 0.85 | ALDH1A1 (0.56) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7653857 | 0.76 | ALDH1A1 (0.52) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL4324973 | 0.71 | KDM4E (0.68) | KMT2AMEN1MAPTALDH1A1CHRNA7 | |
| SCHEMBL7162115 | 0.71 | ALDH1A1 (0.39) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL27582567 | 0.71 | KMT2A (0.60) | KMT2AMEN1MAPTALDH1A1CHRNA7 | |
| SCHEMBL18025321 | 0.70 | MAPT (0.76) | KMT2AMEN1MAPTALDH1A1CHRNA7 | |
| SCHEMBL4555009 | 0.70 | MAPT (0.76) | KMT2AMEN1MAPTALDH1A1CHRNA7 | |
| SCHEMBL26816572 | 0.70 | ALDH1A1 (0.61) | KMT2AMEN1MAPTALDH1A1CHRNA7 | |
| SCHEMBL8118521 | 0.70 | ALDH1A1 (0.65) | KMT2AMEN1MAPTALDH1A1CHRNA7 | |
| SCHEMBL6816388 | 0.69 | MAPT (0.74) | KMT2AMEN1MAPTALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |