Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218149 | 0.82 | FFAR1 (0.55) | ALDH1A1CES2CES1KMT2ALCK | |
| SCHEMBL11736400 | 0.78 | ANPEP (0.50) | SMN1; SMN2ALDH1A1CES2CES1LCK | |
| SCHEMBL12276603 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1CES2CES1KMT2A | |
| SCHEMBL1170312 | 0.71 | FFAR1 (0.68) | SMN1; SMN2ALDH1A1KMT2ASTAT3FFAR1 | |
| SCHEMBL7835806 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1KMT2ASTAT3FFAR1 | |
| Hydrochloric Acid SCHEMBL3043801 | 0.69 | FFAR1 (0.65) | SMN1; SMN2ALDH1A1KMT2ASTAT3FFAR1 | |
| SCHEMBL8746034 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1KMT2ASTAT3FFAR1 | |
| SCHEMBL7397475 | 0.69 | LCK (0.37) | CES2CES1LCKFYNDAO | |
| SCHEMBL7397471 | 0.69 | LCK (0.37) | CES2CES1LCKFYNDAO | |
| SCHEMBL26629077 | 0.69 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1LCKFYNDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | claimed |