Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367430 | 0.84 | CYP1A2 (0.57) | CYP1A2CYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL13476109 | 0.83 | CYP2A6 (0.57) | CYP1A2CYP2A6ALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL7260877 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL7260880 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP2A6ALDH1A1HPGDKDM4E | |
| SCHEMBL8852070 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL8851829 | 0.80 | CYP1A2 (0.48) | CYP1A2CYP2A6ALDH1A1HPGDKDM4E | |
| SCHEMBL11055022 | 0.79 | ATM (0.47) | CYP1A2CYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL18377978 | 0.79 | GPR84 (0.41) | CYP1A2CYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL20799527 | 0.79 | NQO2 (0.52) | CYP1A2CYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL7653940 | 0.79 | ALDH1A1 (0.39) | CYP1A2CYP2A6ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |