Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538635 | 0.77 | ALDH1A1 (0.50) | EHMT2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL2535132 | 0.76 | EHMT2 (0.47) | HCRTR1HCRTR2EHMT2KMT2AMEN1 | |
| SCHEMBL2535135 | 0.76 | EHMT2 (0.47) | HCRTR1HCRTR2EHMT2KMT2AMEN1 | |
| SCHEMBL21538655 | 0.75 | LMNA (0.50) | HCRTR1HCRTR2EHMT2KMT2AMEN1 | |
| SCHEMBL11069497 | 0.75 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9820787 | 0.74 | HCRTR2 (0.46) | HCRTR1HCRTR2EHMT2KMT2AMEN1 | |
| SCHEMBL8094843 | 0.73 | EHMT2 (0.45) | HCRTR1HCRTR2EHMT2KMT2AMEN1 | |
| SCHEMBL7498416 | 0.73 | EHMT2 (0.45) | EHMT2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9631715 | 0.73 | EHMT2 (0.45) | EHMT2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3627524 | 0.73 | EHMT2 (0.45) | EHMT2KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407228-B1 | MIXING ISOCYANATE WITH VINYL ETHER; CYCLIZATION | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2002-06-18 | — | — | US | disclosed |