Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656982 | 0.98 | CES2 (0.52) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9279451 | 0.83 | CES2 (0.49) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29459735 | 0.82 | CES2 (0.65) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL777802 | 0.82 | CES2 (0.65) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28093052 | 0.78 | CES1 (0.38) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13610143 | 0.78 | CES2 (0.59) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27463255 | 0.78 | MEN1 (0.62) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31240544 | 0.77 | CES2 (0.57) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL271808 | 0.77 | CES1 (0.54) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7929773 | 0.76 | CES2 (0.57) | CES2CES1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344360-B1 | INDICATOR WITH BORONATE, ARSENITE, AND/OR GERMANATE GROUP; GLUCOSE DETECTION; MEDICINE, AGRICULTURE | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2002-02-05 | — | — | US | disclosed |