SCHEMBL7929773

SCHEMBL7929773

CC(=O)OC(=O)c1ccc2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.53
HPGD P15428 3/20 0.53
KDM4E B2RXH2 2/20 0.53
NPC1 O15118 5/20 0.51
RAB9A P51151 5/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
EGFR P00533 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
PKM P14618 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
JAK1 P23458 1/20 0.49
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6941398 0.92 PTPN11 (0.46) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL29459735 0.88 CES2 (0.65) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL777802 0.88 CES2 (0.65) CES2CES1SMN1; SMN2HPGDKDM4E
Beta-Naphtoic Acid SCHEMBL27832624 0.84 KDM4E (0.56) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL13610143 0.83 CES2 (0.59) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL27463255 0.83 MEN1 (0.62) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL22880636 0.83 CES2 (0.50) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL29600926 0.83 CES2 (0.50) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL31240544 0.82 CES2 (0.57) CES2CES1SMN1; SMN2HPGDKDM4E
SCHEMBL16856755 0.82 SMN1; SMN2 (0.55) CES2CES1SMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333560-A Method for preparing spiro β -lactam 合肥工业大学 2020-06-26 CN disclosed
EP-1096855-A1 HERBICIDES WITH SUBSTITUTED PHENYLSULFONYLUREAS FOR CONTROLLING WEEDS IN RICE Aventis CropScience GmbH (DE) 2001-05-09 EP disclosed
WO-2000003597-A1 HERBICIDES WITH SUBSTITUTED PHENYLSULFONYLUREAS FOR CONTROLLING WEEDS IN RICE AVENTIS CROPSCIENCE GMBH (DE) 2000-01-27 WO disclosed
EP-0973722-A1 BETA KETOESTER COMPOSITIONS AND METHOD OF MANUFACTURE THE PROCTER & GAMBLE COMPANY (US) 2000-01-26 EP disclosed
CN-1233284-A Fragrance delivery system for liquid detergent compositions PROCTER & GAMBLE (US) 1999-10-27 CN disclosed
WO-1998045245-A1 BETA KETOESTER COMPOSITIONS AND METHOD OF MANUFACTURE THE PROCTER & GAMBLE COMPANY (US) 1998-10-15 WO disclosed