Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604917 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTABCB11F2LMNA | |
| SCHEMBL5514917 | 0.75 | TP53 (0.42) | ALDH1A1MAPTPTGS1RNPEPSLC7A5 | |
| SCHEMBL13542998 | 0.75 | TP53 (0.42) | ALDH1A1MAPTPTGS1RNPEPSLC7A5 | |
| SCHEMBL4839860 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPTPTGS1SLC7A5TP53 | |
| SCHEMBL589941 | 0.71 | — | — | |
| SCHEMBL4056553 | 0.71 | — | — | |
| SCHEMBL4058928 | 0.71 | — | — | |
| SCHEMBL25004681 | 0.70 | TSHR (0.47) | ALDH1A1MAPTCYP2C9PTGS1SLC7A5 | |
| SCHEMBL22355731 | 0.70 | TP53 (0.38) | ALDH1A1MAPTPTGS1SLC7A5TP53 | |
| Cadaverine Tartrate SCHEMBL30041704 | 0.70 | TSHR (0.56) | ALDH1A1MAPTKDM4ELMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384065-B1 | CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1076056-A1 | NOVEL SPIRO COMPOUNDS OR SALTS THEREOF AND PREVENTIVES/REMEDIES FOR AUTOIMMUNE DISEASES AND AP-1 INHIBITORS CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
| EP-0792170-A4 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORP (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5783171-A | Radionuclide metal N2 S2 chelates substituted with glucose and biotin moieties | NEORX CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0792170-A1 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0431146-B1 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF PROTEINS | NEORX CORP (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1995002418-A1 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5250666-A | Radionuclide metal chelates for the radiolabeling of proteins | NEORX CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |
| US-5164176-A | Radionuclide metal chelates for the radiolabeling of proteins | NEORX CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0431146-A4 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF PROTEINS | — | 1992-11-04 | — | — | EP | disclosed |
| EP-0431146-A1 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF PROTEINS. | NEORX CORP (US) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990015808-A1 | RADIONUCLIDE METAL CHELATES FOR THE RADIOLABELING OF PROTEINS | NEORX CORPORATION (US) | 1990-12-27 | — | — | WO | disclosed |