Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 18/20 | 0.38 |
| ▸ | FPR1 | P21462 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061790 | 0.83 | CHRNA7 (0.45) | FPR2FPR1 | |
| SCHEMBL7565280 | 0.82 | CHRNA7 (0.48) | — | |
| SCHEMBL7062857 | 0.81 | CHRNB2 (0.45) | FPR2FPR1MCL1 | |
| SCHEMBL7059277 | 0.79 | CHRNB2 (0.43) | FPR2FPR1KDM4EALDH1A1HPGD | |
| SCHEMBL7118756 | 0.79 | MAPK11 (0.42) | FPR2FPR1 | |
| SCHEMBL7589962 | 0.75 | HSD17B10 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL7063163 | 0.74 | CHRNA7 (0.38) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6872639 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6883061 | 0.73 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL7064234 | 0.73 | CHRNA7 (0.39) | KDM4EALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492385-B2 | CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY | 2002-12-10 | — | — | US | claimed |