Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658242 | 0.95 | MAOB (0.38) | CAMK2DIGF1RMAOBSRD5A2LTB4R | |
| SCHEMBL7851518 | 0.93 | PPARG (0.36) | CNR1CNR2PPARGPPARDPPARA | |
| SCHEMBL7663926 | 0.91 | CNR1 (0.37) | CNR1CNR2PPARGPPARDPPARA | |
| SCHEMBL7661734 | 0.91 | MAOB (0.38) | CNR1CNR2PPARGPPARDPPARA | |
| SCHEMBL8368545 | 0.91 | CAMK2D (0.38) | CNR1CNR2CAMK2DPPARGPPARD | |
| SCHEMBL7657833 | 0.87 | MAOB (0.36) | IGF1RMAOBSRD5A2LTB4RLTB4R2 | |
| SCHEMBL8515918 | 0.87 | IGF1R (0.39) | CNR1CNR2CAMK2DPPARGPPARD | |
| SCHEMBL7664668 | 0.86 | MAOB (0.40) | PPARGIGF1RMAOBALDH1A1LMNA | |
| SCHEMBL7657954 | 0.86 | MAOB (0.38) | PPARGPPARDPPARAIGF1RMAOB | |
| SCHEMBL8362233 | 0.86 | CAMK2D (0.38) | CAMK2DIGF1RMAOBSRD5A2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |
| EP-1071683-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999046264-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |