Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 8/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516735 | 0.95 | IGF1R (0.40) | IGF1RCAMK2DP2RY14PPARGPPARD | |
| SCHEMBL8516793 | 0.88 | CAMK2D (0.48) | CAMK2DCNR1CNR2 | |
| SCHEMBL8368545 | 0.87 | CAMK2D (0.38) | IGF1RCAMK2DP2RY14PPARGPPARD | |
| SCHEMBL7654026 | 0.87 | CNR1 (0.38) | IGF1RCAMK2DPPARGPPARDPPARA | |
| SCHEMBL8516344 | 0.86 | CAMK2D (0.40) | CAMK2DCNR2 | |
| SCHEMBL8516977 | 0.85 | CAMK2D (0.46) | CAMK2DCNR1CNR2 | |
| SCHEMBL8516619 | 0.85 | ASH1L (0.43) | CAMK2DMAPT | |
| SCHEMBL7851518 | 0.84 | PPARG (0.36) | IGF1RPPARGPPARDPPARACNR1 | |
| Acetic Acid SCHEMBL8515922 | 0.83 | IGF1R (0.40) | IGF1RCAMK2DP2RY14PPARGPPARD | |
| SCHEMBL8516993 | 0.83 | CAMK2D (0.37) | CAMK2DCNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |