Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814905 | 0.88 | NPC1 (0.58) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL7654038 | 0.83 | MAPT (0.41) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6819700 | 0.82 | MAPT (0.52) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6815054 | 0.82 | GRM4 (0.58) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6814300 | 0.80 | DHODH (0.56) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6815736 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6811608 | 0.78 | GRM4 (0.51) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6811246 | 0.77 | ALDH1A1 (0.67) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL6814383 | 0.76 | NPC1 (0.55) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6814740 | 0.75 | ALDH1A1 (0.59) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |