Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814913 | 0.89 | NPC1 (0.52) | MAPTKMT2AMEN1PNLIPNPC1 | |
| SCHEMBL6819706 | 0.84 | RAB9A (0.44) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7654030 | 0.83 | MEN1 (0.49) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6814307 | 0.82 | DHODH (0.50) | MAPTKMT2AMEN1PNLIPNPC1 | |
| SCHEMBL6815742 | 0.81 | APEX1 (0.42) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6815060 | 0.79 | NPC1 (0.52) | MAPTKMT2AMEN1PNLIPNPC1 | |
| SCHEMBL6814389 | 0.79 | NPC1 (0.53) | MAPTKMT2AMEN1PNLIPNPC1 | |
| SCHEMBL6811612 | 0.79 | GRM4 (0.46) | MAPTKMT2AMEN1PNLIPNPC1 | |
| SCHEMBL6815406 | 0.78 | FADS1 (0.58) | MAPTKMT2AMEN1PNLIPNPC1 | |
| SCHEMBL7948376 | 0.77 | AVPR2 (0.39) | MAPTKMT2ANPC1RAB9ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |