Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15492070 | 0.85 | HPGD (0.48) | MEN1KMT2AMAPK1HSD17B10POLB | |
| SCHEMBL11820042 | 0.82 | KMT2A (0.45) | MEN1KMT2ARXFP1MAPK1HSD17B10 | |
| SCHEMBL14597968 | 0.81 | HDAC1 (0.67) | MEN1KMT2ARXFP1MAPK1HSD17B10 | |
| SCHEMBL13007428 | 0.80 | MEN1 (0.46) | MEN1KMT2ARXFP1HSD17B10TSHR | |
| SCHEMBL6940053 | 0.79 | CASP3 (0.58) | RXFP1LMNAGRM5 | |
| SCHEMBL16891467 | 0.79 | POLB (0.46) | MEN1KMT2AMAPK1POLBLMNA | |
| SCHEMBL18132362 | 0.79 | CACNA1G (0.60) | MEN1KMT2ARXFP1MAPK1HSD17B10 | |
| SCHEMBL12700357 | 0.79 | CA1 (0.57) | MEN1KMT2ARXFP1MAPK1HSD17B10 | |
| SCHEMBL7549204 | 0.78 | MAPK1 (0.50) | MEN1KMT2ARXFP1MAPK1HSD17B10 | |
| SCHEMBL31753576 | 0.77 | KMT2A (0.70) | MEN1KMT2ARXFP1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |