Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | DDO | Q99489 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559597 | 0.80 | RAB9A (0.76) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7847012 | 0.79 | KDM4E (0.63) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL31146266 | 0.78 | KDM4E (0.65) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL14485203 | 0.78 | KDM4E (0.65) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL15375702 | 0.77 | KDM4E (1.00) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7436988 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1POLBGAAHTT | |
| SCHEMBL20669916 | 0.77 | DAO (0.59) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL377487 | 0.76 | ALDH1A1 (0.68) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL31192183 | 0.76 | ALDH1A1 (0.68) | RAB9AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2754183 | 0.76 | KDM4E (1.00) | RAB9AKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |