SCHEMBL7654178

SCHEMBL7654178

CCCCC1(CCCC)NSc2ccc(N(C)C)cc2[C@@H](c2cccc(N)c2)[C@H]1O

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7848295 0.89 SLC10A2 (0.63) SLC10A2
SCHEMBL7648342 0.80 SLC10A2 (0.66) SLC10A2
SCHEMBL7850994 0.79 SLC10A2 (1.00) SLC10A2
SCHEMBL347340 0.72 SLC10A2 (1.00) SLC10A2
SCHEMBL10013953 0.72 SLC10A2 (1.00) SLC10A2
SCHEMBL7853297 0.71 SLC10A2 (1.00) SLC10A2
SCHEMBL12196445 0.70 SLC10A2 (0.93) SLC10A2
SCHEMBL12196461 0.70 SLC10A2 (0.93) SLC10A2
SCHEMBL19789661 0.70 SLC10A2 (0.62) SLC10A2
SCHEMBL12196590 0.70 SLC10A2 (0.93) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002536440-A 2002-10-29 JP claimed
EP-1155007-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. Searle LLC (US) 2001-11-21 EP claimed
WO-2000047568-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. SEARLE LLC (US) 2000-08-17 WO claimed
EP-1155007-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. Searle LLC (US) 2001-11-21 EP disclosed
WO-2000047568-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. SEARLE LLC (US) 2000-08-17 WO disclosed