SCHEMBL7848295

SCHEMBL7848295

CCCCC1(CCCC)NSc2ccc(N(C)C)cc2[C@@H](c2ccccc2)[C@H]1O

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7654178 0.89 SLC10A2 (0.66) SLC10A2
SCHEMBL12067865 0.79 SLC10A2 (0.63) SLC10A2
SCHEMBL7673034 0.77 SLC10A2 (1.00) SLC10A2
SCHEMBL21085599 0.69 SLC10A2 (0.61) SLC10A2
SCHEMBL7655202 0.69 SLC10A2 (0.64) SLC10A2
SCHEMBL9961477 0.69 SLC10A2 (0.61) SLC10A2
SCHEMBL7648342 0.68 SLC10A2 (0.66) SLC10A2
SCHEMBL7850994 0.68 SLC10A2 (1.00) SLC10A2
SCHEMBL9961496 0.67 SLC10A2 (1.00) SLC10A2
SCHEMBL7651279 0.67 SLC10A2 (0.67) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155007-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. Searle LLC (US) 2001-11-21 EP disclosed
WO-2000047568-A2 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES G.D. SEARLE LLC (US) 2000-08-17 WO disclosed