Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 10/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351009 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALDH2LMNAEGLN1ALKBH5 | |
| SCHEMBL20528837 | 0.72 | ECE1 (0.36) | LMNAEGLN1ALKBH5SUCNR1PHF8 | |
| SCHEMBL11240437 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNATSHR | |
| SCHEMBL18908612 | 0.72 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL14205321 | 0.71 | FFAR3 (0.52) | ALDH1A1ALDH2SLC22A6PHF8KDM4A | |
| SCHEMBL23901176 | 0.70 | ALDH1A1 (0.34) | ALDH1A1ALDH2LMNANFKB1 | |
| SCHEMBL3485719 | 0.70 | TSHR (0.48) | ALDH1A1ALDH2LMNAEGLN1ALKBH5 | |
| SCHEMBL14566299 | 0.69 | ALDH1A1 (0.48) | ALDH1A1ALDH2LMNAEGLN1ALKBH5 | |
| SCHEMBL8068893 | 0.69 | AKR1B1 (0.60) | ALDH1A1SLC22A6PHF8KDM4CKDM5A | |
| Succinic Acid SCHEMBL2596564 | 0.68 | LMNA (0.69) | ALDH1A1LMNAEGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787015-B1 | SYNTHESIS OF TYPHOID FEVER VACCINE FROM A PLANT OR FRUIT POLYSACCHARIDE | US GOV HEALTH & HUMAN SERV (US) | 2002-02-27 | — | — | EP | claimed |
| US-5738855-A | O-ACETYLATING A PLANT, FRUIT OR SYNTHETIC OLIGO OR POLYGALACTURONATE, CONJUGATING THE MODIFIED PLANT, FRUIT OR POLY OR OLIGOGALACTURONATE TO A CARRIER WHICH IS IMMUNOGENIC AGAINST SALMONELLA TYPHI | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-04-14 | — | — | US | claimed |
| EP-0787015-A1 | SYNTHESIS OF TYPHOID FEVER VACCINE FROM A PLANT OR FRUIT POLYSACCHARIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-08-06 | — | — | EP | claimed |
| WO-1996011709-A1 | SYNTHESIS OF TYPHOID FEVER VACCINE FROM A PLANT OR FRUIT POLYSACCHARIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-04-25 | — | — | WO | claimed |