Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754206 | 0.83 | MAOB (0.82) | MAOBMAOANR4A2PARP10 | |
| SCHEMBL751930 | 0.81 | KDM4E (0.57) | MAOBMAOACYSLTR2CYSLTR1 | |
| SCHEMBL751929 | 0.81 | KDM4E (0.57) | MAOBMAOACYSLTR2CYSLTR1 | |
| SCHEMBL754649 | 0.80 | MAOB (0.49) | MAOBMAOANR4A2CYSLTR2CYSLTR1 | |
| SCHEMBL756373 | 0.80 | MAOB (0.49) | MAOBMAOACYSLTR2CYSLTR1CTSL | |
| SCHEMBL17907495 | 0.79 | CYSLTR2 (0.56) | MAOBMAOACYSLTR2CYSLTR1 | |
| SCHEMBL17907496 | 0.79 | CYSLTR2 (0.56) | MAOBMAOACYSLTR2CYSLTR1 | |
| SCHEMBL3228412 | 0.78 | MAOB (0.61) | MAOBMAOANR4A2PARP10 | |
| SCHEMBL31228112 | 0.78 | MCL1 (0.67) | MAOBMAOANR4A2 | |
| SCHEMBL17922020 | 0.78 | MAOB (0.38) | MAOBMAOACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-2266958-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2010-12-29 | — | — | EP | disclosed |