Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765433 | 0.78 | MAOB (0.61) | MAOBMAOACYSLTR1CYSLTR2 | |
| SCHEMBL12324647 | 0.65 | FADS1 (0.45) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL17864853 | 0.63 | MAOA (0.42) | MAOBMAOACYSLTR1KDM4EMEN1 | |
| SCHEMBL17848424 | 0.63 | MAOB (0.44) | MAOBMAOACYSLTR1KDM4EMEN1 | |
| SCHEMBL17848427 | 0.63 | MAOB (0.44) | MAOBMAOACYSLTR1KDM4EMEN1 | |
| SCHEMBL14771365 | 0.63 | MAOB (0.40) | MAOBMAOAALDH1A1HPGDMAPK1 | |
| SCHEMBL12324847 | 0.61 | MAPT (0.57) | MAOBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL751929 | 0.61 | KDM4E (0.57) | MAOBMAOACYSLTR1KDM4EALDH1A1 | |
| SCHEMBL754206 | 0.60 | MAOB (0.82) | MAOBMAOA | |
| SCHEMBL12324652 | 0.60 | SLC5A1 (0.46) | MAOBMEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |