SCHEMBL7654371

SCHEMBL7654371

FN(F)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 4/20 0.38
CYP2A6 P11509 4/20 0.35
CYP1A2 P05177 4/20 0.35
CYP2C19 P33261 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
PNMT P11086 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
IDO1 P14902 1/20 0.33
HIF1A Q16665 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
NR4A2 P43354 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6354181 0.82 TSHR (0.53) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL28344467 0.81 TSHR (0.45) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL437240 0.78 APOBEC3G (0.33) TSHRALDH1A1CYP2A6SMN1; SMN2
SCHEMBL8525837 0.77 CYP1A2 (0.36) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL11206197 0.76 TSHR (0.45) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL174758 0.74 TSHR (0.50) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL25740915 0.74 ALDH1A1 (0.45) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL29049714 0.72 TSHR (0.47) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL14318421 0.72 TSHR (0.47) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL11447749 0.72 TSHR (0.47) TSHRLMNAALDH1A1CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372030-B1 INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID XEROX CORPORATION 2002-04-16 US claimed
EP-0794936-B1 METHOD FOR PREPARING FLUOROANILINES FROM NITROFLUOROBENZENE COMPOUNDS RHODIA CHIMIE SA (FR) 1999-03-17 EP disclosed
US-5856577-A Process for the preparation of fluoroanilines from fluorinated nitrated benzene compounds RHONE-POULENC CHIMIE (FR) 1999-01-05 US disclosed
EP-0875497-A2 Method for preparing fluoroanilines from nitrofluorobenzene compounds RHODIA CHIMIE (FR) 1998-11-04 EP disclosed
EP-0794936-A1 METHOD FOR PREPARING FLUOROANILINES FROM NITROFLUOROBENZENE COMPOUNDS RHONE-POULENC CHIMIE (FR) 1997-09-17 EP disclosed
WO-1996016926-A1 METHOD FOR PREPARING FLUOROANILINES FROM NITROFLUOROBENZENE COMPOUNDS RHONE-POULENC CHIMIE (FR) 1996-06-06 WO disclosed