Biphenyl

Biphenyl

SCHEMBL7654563

CC1=C(C)C(C)C([Hf](NC2CC2)[SiH](c2ccccc2)c2ccccc2)=C1C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.33

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7651916 0.95 MEN1 (0.33) MEN1KMT2A
Biphenyl SCHEMBL7648729 0.95 ALDH1A1 (0.36) MEN1RAB9AKMT2ACNR1CNR2
Biphenyl SCHEMBL7655489 0.94 ALDH1A1 (0.35) MEN1RAB9AKMT2ACNR1CNR2
Biphenyl SCHEMBL7653402 0.94 ALDH1A1 (0.35) MEN1RAB9AKMT2ACNR1CNR2
Biphenyl SCHEMBL7649450 0.94 ALDH1A1 (0.35) MEN1RAB9AKMT2ACNR1CNR2
Biphenyl SCHEMBL7651812 0.94 ALDH1A1 (0.35) MEN1RAB9AKMT2ACNR1CNR2
Hydrochloric Acid SCHEMBL6864361 0.90 GAA (0.31) RAB9A
Hydrochloric Acid SCHEMBL6852497 0.89 LMNA (0.32) MEN1RAB9AKMT2A
Biphenyl SCHEMBL7648978 0.87 MEN1 (0.34) MEN1RAB9AKMT2ACNR1CNR2
Biphenyl SCHEMBL7649693 0.82 MEN1 (0.35) MEN1RAB9AKMT2ACNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423795-B1 USING COORDINATION CATALYST EXXONMOBIL CHEMICAL PATENTS INC. 2002-07-23 US disclosed
US-RE37788-E1 Monocyclopentadienyl metal compounds for ethylene-α-olefin-copolymer production catalysts EXXON CHEMICAL PATENTS, INC. 2002-07-09 US disclosed
US-5621126-A METAL COMPLEX WITH CYCLOPENTADIENE CONTAINS AN AMIDO GROUP HAVING ALIPHATIC OR ALICYCLIC HYDROCARBYL GROUP COVALENTLY BONDED THERETO THROUGH A PRIMARY OR SECONDARY CARBON ATOM; USED AS POLYMERIZATION CATALYST EXXON CHEMICAL PATENTS INC. (US) 1997-04-15 US disclosed