Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652169 | 0.83 | BCHE (0.56) | ACHE | |
| SCHEMBL7677099 | 0.81 | METAP1 (0.40) | ACHE | |
| SCHEMBL4843083 | 0.78 | METAP1 (0.58) | ACHE | |
| SCHEMBL4834272 | 0.69 | METAP1 (0.60) | ACHE | |
| SCHEMBL9581596 | 0.69 | BCHE (0.62) | ACHE | |
| SCHEMBL11668425 | 0.67 | MGLL (0.77) | — | |
| SCHEMBL12306069 | 0.67 | ACHE (0.44) | ACHE | |
| SCHEMBL4198622 | 0.67 | ACHE (0.56) | ACHE | |
| Acetic Acid SCHEMBL29374009 | 0.67 | ACHE (0.60) | ACHE | |
| Acetic Acid SCHEMBL27493902 | 0.67 | ACHE (0.60) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413986-B1 | ALZHEIMER'S DISEASE | AVENTIS PHARMACEUTICALS INC. | 2002-07-02 | — | — | US | claimed |
| US-6413986-B1 | ALZHEIMER'S DISEASE | AVENTIS PHARMACEUTICALS INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0535496-A1 | (1-Indanon-2yl)methylpiperidines, intermediates and a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-07 | — | — | EP | disclosed |