Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654770 | 1.00 | ADORA3 (0.70) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL12521613 | 0.86 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL31037024 | 0.85 | ADORA2A (0.70) | ADORA2A | |
| SCHEMBL5983227 | 0.85 | PNP (0.72) | ADORA3ADORA2AADORA1RXFP1 | |
| SCHEMBL7655056 | 0.85 | PNP (0.72) | ADORA3ADORA2AADORA1RXFP1 | |
| SCHEMBL5983223 | 0.85 | PNP (0.72) | ADORA3ADORA2AADORA1RXFP1 | |
| SCHEMBL17921081 | 0.85 | PNP (0.72) | ADORA3ADORA2AADORA1RXFP1 | |
| SCHEMBL7655065 | 0.85 | PNP (0.72) | ADORA3ADORA2AADORA1RXFP1 | |
| SCHEMBL1998269 | 0.85 | PNP (0.72) | ADORA3ADORA2AADORA1RXFP1 | |
| SCHEMBL23982119 | 0.84 | PMP22 (0.70) | ADORA3ADORA2AADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498241-B1 | 2-deoxy-isoguanosines isosteric analogues and isoguanosine derivatives as well as their synthesis | ROCHE DIAGNOSTICS GMBH (DE) | 2002-12-24 | — | — | US | disclosed |