Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650536 | 0.96 | GPR119 (0.55) | GPR119FAAHMAP4K4CKS1BSKP1 | |
| SCHEMBL3486872 | 0.85 | GPR119 (0.73) | GPR119MAP4K4 | |
| SCHEMBL24671505 | 0.83 | GPR119 (0.52) | GPR119FAAHKDM4EPKM | |
| SCHEMBL30066214 | 0.83 | GPR119 (0.52) | GPR119FAAHKDM4EPKM | |
| SCHEMBL6975264 | 0.82 | GPR119 (0.54) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL25903527 | 0.82 | GPR119 (0.55) | GPR119FAAHCKS1BSKP1SKP2 | |
| SCHEMBL7655982 | 0.82 | GPR119 (0.48) | GPR119FAAHMAP4K4CKS1BSKP1 | |
| SCHEMBL31584217 | 0.81 | GPR119 (0.50) | GPR119FAAHKDM4EPKM | |
| SCHEMBL13591277 | 0.80 | GPR119 (0.50) | GPR119CKS1BSKP1SKP2CHRM4 | |
| SCHEMBL29132280 | 0.79 | GPR119 (0.52) | GPR119FAAHCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |