Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103639 | 0.80 | — | — | |
| SCHEMBL5973624 | 0.77 | — | — | |
| SCHEMBL7565653 | 0.74 | SOAT2 (0.63) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL8343292 | 0.74 | SOAT2 (0.42) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL9136110 | 0.73 | — | — | |
| SCHEMBL9452038 | 0.72 | — | — | |
| SCHEMBL9136927 | 0.71 | — | — | |
| SCHEMBL7108589 | 0.71 | — | — | |
| SCHEMBL9137804 | 0.71 | — | — | |
| SCHEMBL9138808 | 0.71 | LPAR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263421-A2 | THE DUAL INHIBITOR OF CHOLESTERYL ESTER AND WAX ESTER SYNTHESIS AVASIMIBE FOR TREATING SEBACEOUS GLAND DISORDERS | Warner-Lambert Company LLC (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001056556-A2 | DUAL INHIBITORS OF CHOLESTERYL ESTER AND WAX ESTER SYNTHESIS FOR SEBACEOUS GLAND DISORDERS | WARNER-LAMBERT COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |