Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15227104 | 0.79 | — | — | |
| SCHEMBL7097325 | 0.77 | THRB (0.33) | THRB | |
| SCHEMBL7652304 | 0.76 | THRB (0.32) | THRB | |
| SCHEMBL7653132 | 0.74 | THRB (0.31) | THRB | |
| SCHEMBL9048512 | 0.74 | HSD17B10 (0.37) | THRB | |
| SCHEMBL7653955 | 0.74 | THRB (0.31) | THRB | |
| SCHEMBL17350421 | 0.73 | — | — | |
| SCHEMBL3757668 | 0.72 | — | — | |
| SCHEMBL7415858 | 0.71 | HSD17B10 (0.34) | — | |
| SCHEMBL14992219 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002536440-A | — | — | 2002-10-29 | — | — | JP | claimed |
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | claimed |