Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PPM1A | P35813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659168 | 0.99 | PDE2A (0.44) | PDE2ATHRAPDK2THRBNR5A1 | |
| SCHEMBL7655752 | 0.96 | PDE2A (0.43) | PDE2ASLC6A2SLC6A4L3MBTL1FAAH | |
| SCHEMBL7667030 | 0.90 | CYP1A1 (0.46) | PDE2APDK2SLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL16141274 | 0.90 | L3MBTL1 (0.47) | PDE2ASLC6A2SLC6A4L3MBTL1FAAH | |
| SCHEMBL8724311 | 0.87 | NR5A1 (0.55) | THRANR5A1TSHRMTNR1A | |
| SCHEMBL12259989 | 0.85 | NR5A1 (0.53) | THRANR5A1TSHRMTNR1A | |
| SCHEMBL12259997 | 0.85 | NR5A1 (0.53) | THRANR5A1TSHRMTNR1A | |
| SCHEMBL12278287 | 0.85 | NR5A1 (0.53) | THRANR5A1TSHRMTNR1A | |
| SCHEMBL7658329 | 0.84 | PDK2 (0.44) | THRAPDK2THRBNR5A1TSHR | |
| SCHEMBL7667584 | 0.84 | MAPT (0.51) | L3MBTL1PPM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |