Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663254 | 0.90 | ALDH1A1 (0.47) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7661471 | 0.88 | CYP3A4 (0.53) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7654193 | 0.86 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7658461 | 0.86 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7657150 | 0.84 | CYP3A4 (0.49) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7659372 | 0.80 | PLAU (0.61) | RAB9ANPC1GAASGMS2PLAU | |
| SCHEMBL7662346 | 0.79 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7656226 | 0.77 | F2 (0.55) | RAB9ANPC1PLAUPLATF2 | |
| SCHEMBL7659362 | 0.76 | CYP2C9 (0.51) | GAAALDH1A1KMT2AMEN1PLAU | |
| SCHEMBL7688990 | 0.76 | F3 (0.63) | F2F10PRSS1PRSS2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |