Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663254 | 0.92 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7662346 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7661471 | 0.91 | CYP3A4 (0.53) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7654193 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7657150 | 0.88 | CYP3A4 (0.49) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7688990 | 0.86 | F3 (0.63) | — | |
| SCHEMBL7656002 | 0.86 | RAB9A (0.45) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7657290 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7659362 | 0.79 | CYP2C9 (0.51) | ALDH1A1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL7679600 | 0.78 | F3 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |