Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 18/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571536 | 0.84 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL6362496 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7571529 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7568704 | 0.81 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL7571526 | 0.79 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL2709199 | 0.79 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL7655900 | 0.79 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7571956 | 0.79 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7568662 | 0.77 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL13753359 | 0.76 | HPGD (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |