SCHEMBL7656224 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GABRG2	P18507	20/20	0.57

▸	GABRB3	P28472	20/20	0.57

▸	GABRA5	P31644	20/20	0.57

▸	GABRA1	P14867	19/20	0.57

▸	GABRA3	P34903	19/20	0.57

▸	GABRA2	P47869	19/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7400032	0.79	GABRA1 (0.57)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL7662252	0.77	GABRG2 (0.58)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL7545847	0.73	GABRG2 (0.55)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL7658660	0.73	GABRG2 (0.55)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL10969056	0.73	RXFP1 (0.46)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL7399747	0.73	GABRG2 (0.80)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL2647354	0.72	GABRG2 (0.60)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL10965944	0.68	RXFP1 (0.44)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL1205699	0.68	GABRG2 (0.32)	GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL21009025	0.61	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6465462-B1	COGNITION ENHANCEMENT FOR DEMENTING ILLNESSES SUCH AS ALZHEIMER'S DISEASE	MERCK SHARP & DOHME LTD.	2002-10-15	—	—	US	disclosed