Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935557 | 0.81 | LMNA (0.47) | LMNAKDM4EADRB1ADRA1ATSHR | |
| SCHEMBL7071503 | 0.78 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL31085235 | 0.74 | LMNA (0.44) | KMT2AMEN1UGT2B7BRD4BRD2 | |
| SCHEMBL9331663 | 0.73 | UGT2B7 (0.56) | KMT2AMEN1UGT2B7BRD4BRD2 | |
| SCHEMBL2812852 | 0.73 | UGT2B7 (0.56) | KMT2AMEN1UGT2B7BRD4BRD2 | |
| SCHEMBL9334664 | 0.73 | UGT2B7 (0.56) | KMT2AMEN1UGT2B7BRD4BRD2 | |
| SCHEMBL9331659 | 0.73 | UGT2B7 (0.56) | KMT2AMEN1UGT2B7BRD4BRD2 | |
| SCHEMBL24081423 | 0.73 | MEN1 (0.41) | KMT2AMEN1UGT2B7BRD4BRD2 | |
| SCHEMBL921104 | 0.71 | ALDH1A1 (0.46) | KMT2AMEN1LMNAKDM4EHTR2A | |
| SCHEMBL26998957 | 0.69 | LMNA (0.41) | KMT2AMEN1UGT2B7BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342613-B1 | REACTING PYROCATECHOL WITH DIHALO- OR DI-ALKOXYALKANE, ACYLATING BENZO(1,3)DIOXOLE DERIVATIVE FORMED IN PRESENCE OF CATALYST, REDUCING TO 5-(ALPHA-HYDROXYALKYL)BENZO(1,3)DIOXOLE | ENDURA S.P.A. (IT) | 2002-01-29 | — | — | US | disclosed |
| EP-1140894-A1 | PROCESS FOR THE SYNTHESIS OF 5-(ALPHA -HYDROXYALKYL) BENZO 1, 3]DIOXOLS | ENDURA S.p.A. (IT) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040575-A1 | PROCESS FOR THE SYNTHESIS OF 5-(α -HYDROXYALKYL) BENZO[1, 3]DIOXOLS | ENDURA S.P.A. (IT) | 2000-07-13 | — | — | WO | disclosed |