Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | HTR7 | P34969 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884099 | 0.90 | DPP4 (0.54) | DPP4HTR1AHTR7ACE | |
| Hydrochloric Acid SCHEMBL10963697 | 0.85 | ACE (0.63) | DPP4ACE | |
| SCHEMBL16229682 | 0.84 | DPP4 (0.54) | DPP4HTR1AHTR7 | |
| SCHEMBL13954202 | 0.83 | DPP4 (0.51) | DPP4HTR1AHTR7ACE | |
| SCHEMBL29195203 | 0.83 | DPP4 (0.53) | DPP4HTR1AHTR7 | |
| SCHEMBL8772866 | 0.82 | DPP4 (0.56) | DPP4HTR1AHTR7ACE | |
| SCHEMBL8772871 | 0.82 | DPP4 (0.56) | DPP4HTR1AHTR7ACE | |
| SCHEMBL683068 | 0.81 | DPP4 (0.50) | DPP4HTR1AHTR7ACE | |
| SCHEMBL14463150 | 0.81 | DPP4 (0.51) | DPP4HTR1AHTR7ACE | |
| SCHEMBL29540069 | 0.81 | DPP4 (0.53) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |